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Manuel Méndez Selected Research

Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)

6/2013Familial porphyria cutanea tarda in Spain: characterization of eight novel mutations in the UROD gene and haplotype analysis of the common p.G281E mutation.
4/2012Molecular analysis of the UROD gene in 17 Argentinean patients with familial porphyria cutanea tarda: characterization of four novel mutations.
8/2010Smoking but not homozygosity for CYP1A2 g-163A allelic variant leads to earlier disease onset in patients with sporadic porphyria cutanea tarda.
2/2004Volatile anaesthetics induce biochemical alterations in the heme pathway in a B-lymphocyte cell line established from hepatoerythropoietic porphyria patients (LBHEP) and in mice inoculated with LBHEP cells.

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Manuel Méndez Research Topics

Disease

7Iron Overload
05/2016 - 01/2008
4Porphyria Cutanea Tarda
06/2013 - 02/2004
4Hemochromatosis (Bronze Diabetes)
03/2011 - 01/2008
3Myocardial Infarction
05/2021 - 01/2013
3Acute Intermittent Porphyria (Porphyria, Acute)
12/2020 - 02/2004
3Porphyrias (Porphyria)
12/2019 - 08/2004
3Erythropoietic Protoporphyria
12/2013 - 09/2007
2Rare Diseases (Rare Disease)
12/2019 - 12/2013
2Anemia
05/2016 - 09/2007
2ST Elevation Myocardial Infarction
07/2014 - 01/2013
2Hypertrichosis
04/2012 - 08/2004
2Hyperferritinemia
06/2011 - 12/2010
2Hepatic Porphyrias (Hepatic Porphyria)
08/2005 - 02/2004
1COVID-19
05/2021
1Cardiogenic Shock
05/2021
1Aneurysm (Aneurysms)
11/2020
1X-linked sideroblastic anemia
05/2016
1Hyponatremia
12/2013
1Thrombosis (Thrombus)
01/2013
1Hyperpigmentation
04/2012
1Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
01/2012
1Metabolic Syndrome (Dysmetabolic Syndrome X)
06/2011
1hereditary Hyperferritinemia with congenital cataracts
12/2010
1Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
12/2010
1Liver Diseases (Liver Disease)
01/2008
1Pain (Aches)
08/2005
1Alcoholism (Alcohol Abuse)
03/2005
1Hepatoerythropoietic Porphyria
02/2004

Drug/Important Bio-Agent (IBA)

5IronIBA
06/2011 - 01/2008
4Heme (Haem)IBA
12/2020 - 02/2004
4Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA
06/2013 - 02/2004
3metal transporting protein 1 (ferroportin)IBA
07/2014 - 12/2010
3PorphyrinsIBA
04/2012 - 02/2004
2EnzymesIBA
12/2020 - 04/2012
2protoporphyrin IXIBA
12/2009 - 09/2007
1Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA
12/2020
1Transcription Factors (Transcription Factor)IBA
05/2016
1Pyridoxine (Pyridoxin)FDA LinkGeneric
05/2016
1TicagrelorIBA
07/2014
1Pharmaceutical PreparationsIBA
07/2014
1Clopidogrel (Plavix)FDA Link
07/2014
1Vitamin DFDA LinkGeneric
12/2013
1Sunscreening Agents (Sunscreens)IBA
12/2013
1MetalsIBA
01/2013
1PorphyrinogensIBA
04/2012
1Protoporphyrinogen Oxidase (Protox)IBA
01/2012
1Transferrin (beta 2 Transferrin)IBA
06/2011
1Ferritins (Ferritin)IBA
12/2010
1Acute-Phase Proteins (Acute-Phase Protein)IBA
12/2010
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
08/2010
1Ferrochelatase (Heme Synthetase)IBA
09/2007
1Analgesics (Analgesic Drugs)IBA
08/2005
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
08/2005
13- (2- hydroxy- 4- (1,1- dimethylheptyl)phenyl)- 4- (3- hydroxypropyl)cyclohexanolIBA
08/2005
1CannabinoidsIBA
08/2005
1Estrogens (Estrogen)FDA Link
03/2005

Therapy/Procedure

2Therapeutics
05/2021 - 01/2008
2Percutaneous Coronary Intervention
05/2021 - 01/2013
2Stents
11/2020 - 01/2013
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
12/2009 - 01/2008
1Length of Stay
12/2013